New Application Note: How chemicals influence cell proliferation – Straightforward cell culture monitoring using CASY TT
A new application note from the Institute of Biophysics of the Leibniz University Hannover describes very clearly how CASY is optimally used to quality control cell culture experiments. The authors describe how they use CASY, to examine influences of drugs on cell cultures, which ought to be used in subsequent experiments – e. g. the investigation of molecular signalling pathways – ..
Do these substances per se have cytotoxic characteristics, do they influence cell growth alone and thus the outcome of the experiment?
Such advance information are mandatory, to get reliable results in cell assays, which require a reliable comparison of differently treated cell populations, ..
The group resolved this problem using the CASY: CASY is ideal to determine cell proliferation after confrontation with the drug by measurement of viable cells. Quickly and easily CASY additionally determines vital cells, dead cells and debris – essential parameters for cell culture quality control.
Read the article here:
Annegret Becker, Almke Bader, Anne Velcro & Inken Hanada |Institute of Biophysics | AG Cellular Physiology & Cellular mechanics | Prof. Dr. Ngezahayo | Leibniz University of Hannover | Germany
Almke Bader and Annegret Becker,
Institute of Biophysics, AG Cellular Physiology & Cellular mechanics Prof. Dr. A. Ngezahayo, Leibniz University of Hannover.
We routinely work with the CASY TT cell counter because it enables the simple and convenient monitoring of our cell cultures. We are able to visualize not only the cell number but also the vital state of our cell cultures. This enables us to easily evaluate the quality of the cells and to reproduce and standardize the cell culture quality for our experiments. Furthermore, due to the possibility to save up to 20 different measurement set-ups, the simultaneous handling of different cell lines is very easy with the CASY TT. Finally, the CASY TT is consistently integrated in our daily laboratory routine.”